Human Anti-GPNMB Recombinant Antibody (clone Glembatumumab)
CAT#: TAB-751
This product is a human IgG2, κ antibody that can recognize human GPNMB.
Tested Data
Gene Expression
SDS-PAGE
Figure 1 GPNMB Recombinant Antibody (TAB-751) in SDS-PAGE
SDS-PAGE analysis of TAB-751 in non-reduced (lane 1) and β-mercaptoethanol-reduced (lane 2) conditions.
SEC-HPLC
Figure 2 GPNMB Recombinant Antibody (TAB-751) in HPLC
The purity of TAB-751 was greater than 95% as determined by SEC-HPLC.
WB
Figure 3 GPNMB Recombinant Antibody (TAB-751) in WB
Western blot analysis was performed by loading 0.1 µg (lane 1), 0.1 µg(lane 2), and 0.6 µg (lane 3) recombinant human GPNMB.
The secondary antibody: HRP-Anti-Human IgG (H+L)
Dot Blot
Figure 4 GPNMB Recombinant Antibody (TAB-751) Dot Blot
Dot Blot analysis of TAB-751 was performed by coating with human GPNMB antigen.
TAB-751 incubation concentration: 2 ng/μL.
The secondary antibody: HRP-Anti-Human IgG (H+L)
ELISA
Figure 5 GPNMB Recombinant Antibody (TAB-751) in ELISA
ELISA analysis of TAB-751 was performed by coating with recombinant human GPNMB antigen.
The secondary antibody: HRP-Anti-Human IgG (H+L)
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RNA Expression
Figure 1 RNA cell line category: Cell line enriched (ASC diff)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000136235-GPNMB
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Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Human
- Type
- Human IgG2, κ
- Specificity
- Human GPNMB
- Species Reactivity
- Human
- Clone
- Glembatumumab
- Applications
- WB, IF, IP, Neut, FuncS, ELISA, FC
Product Property
- Purification
- Protein A/G Purified
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Western Blot, Immunofluorescence, Immunoprecipitation, Neutralization, Functional Assay, Enzyme-linked Immunosorbent Assay, Flow Cytometry.
Target
- Alternative Names
- glycoprotein nmb; NMB; HGFIN; PLCA3; transmembrane glycoprotein NMB; glycoprotein (transmembrane) nmb; glycoprotein nmb-like protein; glycoprotein nonmetastatic melanoma protein B; hematopoietic growth factor inducible neurokinin-1 type; osteoactivin; transmembrane glycoprotein HGFIN
- Gene ID
- 10457
- UniProt ID
- Q14956
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Biosimilar Overview
Please refer to Glembatumumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Glembatumumab.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1138-VHH | Recombinant Anti-Human GPNMB VHH Single Domain Antibody | WB, ICC, ChiP, FA, ELISA | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4197 | Rabbit Anti-GPNMB Recombinant Antibody (clone SI275DS) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0005-LS-F(E) | Rabbit Anti-GPNMB Recombinant Antibody; Fab Fragment (HPAB-0005-LS-F(E)) | FC | Rabbit Fab |
| HPAB-0006-LS-F(E) | Human Anti-GPNMB Recombinant Antibody Fab Fragment (HPAB-0006-LS-F(E)) | ELISA | Human Fab |
| HPAB-1535-FY-S(P) | Human Anti-GPNMB Recombinant Antibody (clone 1.10.2); Fab Fragment | Inhib, ELISA | Human Fab |
| HPAB-1536-FY-S(P) | Human Anti-GPNMB Recombinant Antibody (clone 1.2.2); Fab Fragment | Inhib, ELISA | Human Fab |
| HPAB-1537-FY-S(P) | Human Anti-GPNMB Recombinant Antibody (clone 1.7.1); Fab Fragment | Inhib, ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0005-LS-S(P) | Rabbit Anti-GPNMB Recombinant Antibody; scFv Fragment (HPAB-0005-LS-S(P)) | FC | Rabbit scFv |
| HPAB-0006-LS-S(P) | Human Anti-GPNMB Recombinant Antibody scFv Fragment (HPAB-0006-LS-S(P)) | ELISA | Human scFv |
| HPAB-1535-FY-F(E) | Human Anti-GPNMB Recombinant Antibody (clone 1.10.2); scFv Fragment | Inhib, ELISA | Human scFv |
| HPAB-1536-FY-F(E) | Human Anti-GPNMB Recombinant Antibody (clone 1.2.2); scFv Fragment | Inhib, ELISA | Human scFv |
| HPAB-1537-FY-F(E) | Human Anti-GPNMB Recombinant Antibody (clone 1.7.1); scFv Fragment | Inhib, ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-020CQ | Mouse Anti-GPNMB Recombinant Antibody (clone YC095) | WB, IHC, FC | Mouse IgG2b |
| MOB-122CQ | Rat Anti-GPNMB Recombinant Antibody (clone YC096) | ELISA, WB | Rat IgG2b |
| MOB-123CQ | Rat Anti-GPNMB Recombinant Antibody (clone YC097) | FC | Rat IgG2a |
| HPAB-1535-FY | Human Anti-GPNMB Recombinant Antibody (clone 1.10.2) | Inhib, ELISA | Human IgG |
| HPAB-1536-FY | Human Anti-GPNMB Recombinant Antibody (clone 1.2.2) | Inhib, ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-751 | Afuco™ Anti-GPNMB ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-751) | IF, IP, Neut, FuncS, ELISA | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY944 | Anti-GPNMB Immunohistochemistry Kit | IHC | |
| VS-0525-XY2890 | Anti-Human GPNMB Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY114 | Human Anti-GPNMB scFv-Fc Chimera (VS-0425-FY114) | ELISA, FC | Human IgG2, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC81 | Recombinant Anti-GPNMB Vesicular Antibody, EV Displayed (VS-0425-YC81) | ELISA, FC, Neut, Cell-uptake |
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